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48 ANTIBIOTIC RESISTANCE & STEWARDSHIP Introducing the Hill-Rom® Care Sign Protecting Patients by Anticipating Care to reduce patient falls, infections and patient dissatisfaction. Today, paper signs blanket the healthcare environment. Signs can be inaccurate and relay incorrect information to healthcare providers and visitors. Hill-Rom's Care Sign, a digital signage solution placed at the patient room entryway, corrects this problem with a real-time connection to the EMR to provide accurate patient precautions, allergies, risk and stang information. ©2017 Hill-Rom Services, Inc. ALL RIGHTS RESERVED. 199608 rev 2 04-APR-2017 ENG – US Reducing Fall Risk Improving Infection Control and Protocol Compliance Improving Patient Satisfaction To learn more, visit www.hill-rom.com/care-sign Supporting Key Hospital Initiatives SM Childhood Antibiotic Use Linked to Adult Inflammatory Gut Diseases in New Study By Heather Punke A new study on mice shows antibiotic use early in life could contribute to development of inflammatory bowel disease and other inflammatory diseases like asthma later in life. e research, published in the Journal of Leukocyte Biology, suggests childhood antibiotic use can affect disease development in adulthood, Colby Zaph, PhD, head of the Laboratory of Mucosal Immunity and Inflammation at Monash University in Australia, explained. "is has important ramifications for the use of pre- and probiotics, the admin- istration of antibiotics to neonates and our understanding of how gut bacteria play a critical role in influencing the development of inflam- matory diseases such as IBD," he said. Dr. Zaph and his team tested two groups of mice — one of pregnant females treated with antibiotics during pregnancy and baby mice treat- ed in the first three weeks of life, and a control group of untreated pregnant mice and babies. Baby mice that were treated with antibiotics had reduced levels of gut bacteria, and the immune cells from treated mice induced more rapid and severe disease than those from the control group. "Our intestinal commensal bacteria are now understood to have a ma- jor role in shaping immune health and disease, but the details for this process remain poorly understood," said John Wherry, PhD, deputy editor of the Journal of Leukocyte Biology. "ese new studies provide an important clue as to how the early signals from our gut bacteria shape key immune cells and how these neonatal events can shape dis- ease potential later in life." n Common Antibiotic Ear Drops Up Risk of Perforated Eardrums By Heather Punke A type of antibiotic ear drop commonly prescribed after ear tube surgery may increase the risk of perforated eardrums, according to a study from Gainesville-based University of Florida Health, pub- lished in Clinical Infectious Diseases. UF Health researchers compared the rates of perforat- ed eardrums after using two types of ear drops after ear tube surgery: quinolones and neomycin. They found children who received quinolone ear drops were 60 percent more likely to suffer from a perforated