Issue link: https://beckershealthcare.uberflip.com/i/545703
25 Executive Briefing: Trends in Artificial Disc Replacement Sponsored by: ® Changing clinical landscape For years, spinal fusion has been the domi- nant procedure for cervical spine surgery. While spinal fusion continues to hold the largest market share, tides are changing as non-fusion options are more widely avail- able and accepted in spine practices today. Companies focused on disc replacement, like LDR with its Mobi-C® Cervical Disc, are poised to become leaders in the chang- ing spinal instrumentation market. The Millennium Research Group reported that the global spinal non-fusion market would surpass $1.6 billion by 2022, nearly tripling in size from just a few years ago. By 2020, cervical disc replacement is ex- pected to have 10 percent of the global spine surgery market, according to a Med- Market Diligence report. Patients are demanding alternatives to fu- sion, which limits mobility and could lead to adjacent segment disease. Payers are also more willing to reimburse for disc re- placement devices, giving more patients access to the procedure. There are around 13 million people in the United States who visit their physicians with chronic back pain each year, covering about 60 percent to 80 percent of the adult population. Treating people who suffer from chronic back pain costs around $600 billion per year. Healthcare providers are looking for the best solutions to treat each patient cost-effectively and return them to normal life. Cervical disc replacement could fill those needs for the appropriately indicated pa- tients. Level 1, long-term, five-year safety and efficacy data on both the one and two- level Mobi-C versus traditional cervical fusion This data was first presented at the North American Spine Society (NASS) annual meeting in November 2014, and was the subject of six recent podium presenta- tions at the International Society for the Advancement of Spine Surgery (ISASS) annual meeting in April 2015 in San Di- ego. Conclusions highlighted during the presentations included: • Two-level Mobi-C patients, as com- pared to Anterior Cervical Discec- tomy and Fusion, or ACDF, demon- strated statistically significantly better long-term sustainability of success and clinical outcomes. • Comparing two-level Cervical Total Disc Replacement, or CTDR, and ACDF in the prospective, random- ized study with long-term follow-up, Mobi-C showed statistically signifi- cantly greater clinical improvement in general and disease specific out- come measures compared to ACDF. • In addition, there were statistically significantly fewer primary and adja- cent level reoperations with cervical artificial disc treatment as compared to fusion. "We've been very pleased with our early experience in the U.S. cervical disc mar- ket as it builds on our existing strong pres- ence in anterior cervical fusion with the ROI-C ® Cervical Cage," says Christophe Lavigne, President and Chief Executive Officer of LDR. "In contrast to many spine procedures performed today, cervical disc replacement is supported by an exception- Motion Preservation and the Rise of Disc Replacement "In contrast to many spine procedures performed today, cervical disc replacement is supported by an exceptional library of Level 1 clinical evidence, now including data from the one and two-level Mobi-C IDE trials." — Christophe Lavigne, President and CEO of LDR. Christophe Lavigne