Becker's ASC Review

15 EXECUTIVE BRIEFING EXECUTIVE BRIEFING Narrow Band Imaging ™ offers a brighter experience during procedures Narrow Band Imaging ™ (NBI ™ ) technology has been part of the Olympus platform since 2005 and continues to be an imaging modality offered on the EVIS X1 endoscopy system. NBI technology provides a sharp and clear endoscopic image. 4 "Historically, NBI technology has been used to look at Barrett's esophagus," Mr. Romano said. "Now, NBI technology is increasingly being used in the colon. Using this technology for different procedures and areas of care is helpful in the ASC." Dr. Shehata now uses the EVIS X1 endoscopy system during all of his GI procedures. Its features and functionality are making a positive difference regardless of case type. For example, for patients with Barrett's esophagus, NBI technology quickly directs Dr. Shehata to small lesions in the lower part of the esophagus that need to be biopsied for dysplasia. Improved scope ergonomics may minimize physician injuries and fatigue In addition to incorporating innovative imaging technologies into the EVIS X1 endoscopy system, Olympus has redesigned some of its endoscopes. "Some ASC physicians perform 10 to 20 cases per day. They experience a lot of stress specifically around the wrist, hand and fingers," Mr. Romano said. To help alleviate these issues, Olympus reduced the weight of the EVIS X1 scope control section by 10 percent and made the scope's angulation control knobs and switches more accessible. 5 "Typically, scopes are one-size-fits-all," Mr. Romano said. "The EVIS X1 scope control section has been designed so it's easy for physicians with small hands to access the buttons, valves and switches." The EVIS X1 ™ endoscopy system design supports ASC economics and operations The EVIS X1 endoscopy system can be used with most of the previous generation of Olympus® scopes, the EVIS EXERA ™ III 190 series. 6 ASC physicians can plug compatible 190 series scopes into the CV- 1500 video system center and access the new imaging modalities. "From a financial perspective, ASCs don't have to upgrade everything at once," Mr. Romano said. "They can use existing assets 6 and then upgrade scopes further down the road. Accessing this new technology doesn't have to mean a big, one-time investment." In addition, Olympus has incorporated features into the EVIS X1 endoscopy system that make it particularly well suited for ASC environments. The processor and light source have been combined in one box, which reduces the footprint of the system. 7 To reduce system maintenance, Olympus switched from a xenon light bulb to five LEDs, which have a longer life and consume less energy. 8 In addition, the EVIS X1 endoscopy system is completely digital, with a touch panel and customizable settings for each physician and/or different procedure types. 9 Beyond the features of its new endoscopy system, Olympus provides ASCs with a high level of customized customer service. During the installation process, the sales representative, field service engineer and endoscopy support specialist will show an ASC's staff how to use the CV-1500 video system center, its new imaging technologies and its menu options. Conclusion ASI is an organization that embraces change and innovation. As a result, physicians at ASI are encouraged to learn and utilize new technologies. "Test out the EVIS X1 endoscopy system and you'll see the difference," Mr. Smith said. "You may catch more polyps. But you should see more than you did with the light provided in previous generation systems that might not catch a growth, polyp or lesion." Dr. Shehata emphasized that the "EVIS X1 endoscopy system may help physicians detect more lesions, reduce bleeding and shorten procedure times." "Time is money," he added. "But most importantly, the EVIS X1 endoscopy system may give endoscopists confidence that they didn't miss any lesions, which may help to improve patient outcomes." 2 The EVIS X1 ™ endoscopy system is not designed for cardiac applications. Other combinations of equipment may cause ventricular fibrillation or seriously affect the cardiac function of the patient. Improper use of endoscopes may result in patient injury, infection, bleeding, and/or perforation. Complete indications, contraindications, warnings, and cautions are available in the Instructions for Use (IFU). The positions and statements made herein by ASI are based on ASI's experiences, thoughts and opinions. As with any product, results may vary and the techniques, instruments and settings can vary from facility to facility. You should thoroughly review the relevant user manual(s) for instructions, warnings, and cautions. 4 Data on file with Olympus (DC00489968). 5 Data on file with Olympus (DC00482729, DC00600786, DC00031984, DC00482747, DC00482867, DC00600794, DC00481878, DC00031984 and DC00841888). 6 As defined as compatible in the Instructions for Use (IFU) for the CV-1500 video system center. 7 Data on file with Olympus (DC00436067). 8 Data on file with Olympus (DC00412083 and DC00623365). 9 Data on file with Olympus (DC00460933). At Olympus, we are committed to Our Purpose of making people's lives healthier, safer, and more fulfilling. As a global medical technology company, we partner with healthcare professionals to provide best-in-class solutions and services for early detection, diagnosis, and minimally invasive treatment, aiming to improve patient outcomes by elevating the standard of care in targeted disease states. For more than 100 years, Olympus has pursued a goal of contributing to society by producing products designed with the purpose of delivering optimal outcomes for its customers around the world. For more information, visit www.olympusamerica.com. LCR50660V01

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