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16 PRACTICE MANAGEMENT 35 Orthopedic and Spine Device Companies to Know | 2021 H ere are 35 orthopedic and spine device companies to keep an eye on over the next year. 4Web Medical (Frisco, Texas). 4Web Med- ical uses 3D printing technology to make orthopedic and spine implants. e company was founded in 2008 and has grown to in- clude five FDA-cleared implant systems. In October, 4Web launched a standalone ante- rior lumbar spine system with the first proce- dure being performed by James Lynch, MD, CEO of SpineNevada in Reno. Aesculap Implant Systems (Center Valley, Pa.). Aesculap offers a suite of hip and knee implants, navigation and spine technologies that includes the activL artificial disc. e company's knee portfolio offers advanced surface technology to guard against implant wear and metal ion release. Atec (Carlsbad, Calif.). Atec focuses on de- veloping new approaches for spine surgery. In February, the company opened a new head- quarters in Carlsbad, Calif., to add education space, a biomechanical lab and machining center. e company employs around 300 people and expects to continue building its team this year. Arthrex (Naples, Fla.). Arthrex is a global orthopedic device company focused on ar- throscopy. It develops more than 1,000 prod- ucts and procedures annually. In December, Arthrex launched the SwiveLock ACL repair kit for treating primary ACL tears. Bioventus (Durham, N.C.). Bioventus is a global company focused on minimally inva- sive joint therapies and surgical biologics. e company's orthobiologics products promote bone formation and include allogra and synthetic offerings. e company launched an initial public offering in February. Camber Spine (Prussia, Pa.). Camber Spine develops surgeon-designed minimally inva- sive technologies for treating complex spine disorders. e company has 20 FDA-cleared spine products and more than 28 active or is- sued patents. Camber Spine was established in 2010 and incorporates 3D printing into its implants. ChoiceSpine (Knoxville, Tenn.). Choic- eSpine is a privately held spine implant com- pany founded in 2006. It has a portfolio of regenerative and osteobiologic products, in- cluding a lateral fusion system and implants manufactured with 3D printing technology. e company uses impregnated hydroxyapa- tite with its interbody products. Conformis (Billerica, Mass.). Conformis uses advanced 3D-imaging technology to develop patient-specific knee implants. e company's proprietary iFit Image-to-Implant platform sells joint implants individually sized and shaped to the patient's anatomy for partial and total knee replacements. Conventus Orthopedics (Maple Grove, Minn.). Conventus focuses on 3D fracture fixation technology. In 2020, Conventus ac- quired Flower Orthopedics, which provides sterile packaged, single-use orthopedic sur- gery products. Since then, it has hired two executives to lead sales and research and de- velopment. DePuy Synthes (West Chester, Pa.). DePuy Synthes is part of Johnson & Johnson Med- ical Device Companies. It provides joint re- construction, trauma, spine and sports med- icine products. e DePuy Synthes Attune knee system has been implanted in more than 1 million patients worldwide. DJO (Lewisville, Texas). DJO is an orthope- dic products company with more than 5,000 employees and 1,000 medical devices. It was acquired by Colfax Corp., a diversified tech- nology company, in 2019 and continues to produce orthopedic braces, surgical products and spine technologies. Exactech (Gainesville, Fla.). Exactech de- velops orthopedic implants, instruments and technologies. In February, the company launched the next generation of the Exact- echGPS- guided personalized surgery system for knee and shoulder replacements. Globus Medical (Audubon, Pa.). Globus Medical is a spine device and technology manufacturer. e company has spinal im- plant, robotics and navigation platforms for complex and minimally invasive proce- dures. Globus' spinal robotics technology, ExcelsiusGPS, assists surgeons with pedicle screw placement and provides navigation for transforaminal and lateral lumbar interbody fusions. GS Medical (Mission Viejo, Calif.). GS Medical is a global medical device compa- ny focused on the care of spine disorders, providing various solutions from implants to disposables. GS Medical is dedicated to providing state-of-the-art, innovative spine products for better patient care, working closely with surgeons, distributors and hos- pital partners to create custom solutions that meet their needs. Integra LifeSciences (Princeton, N.J.). In- tegra LifeSciences is a global medical device company with orthopedics, neurosurgery and general and reconstructive surgery prod- ucts. It was founded in 1989 and has grown to include 3,000 employees. In January the company acquired ACell, a regenerative medicine company. Life Spine (Huntley, Ill.). Life Spine was founded in 2004 and has grown to include 70 employees worldwide. e company pro- vides biologics and foot and ankle extremity fixation devices and spinal fusion products. More than 1,000 surgeons from 48 states and 32 countries use Life Spine's products. LimaCorporate (San Daniele del Friuli, It- aly). LimaCorporate is a global orthopedics company focused on joint replacement pro- cedures. It includes shoulder, elbow, hip and knee products. In 2019, LimaCorporate part- nered with New York City-based Hospital for Special Surgery to found an additive manu- facturing 3D-printing facility to customize implants at the hospital. Medacta (Franklin, Tenn.). Medacta of- fers minimally invasive orthopedic surgical products and is known for the minimally invasive anterior hip replacement technique. e company's MySolutions technology of- fers personalized preoperative planning and develops personalized kinematic models and 3D-planning tools for hip, knee, shoulder and spine procedures.