Becker's ASC Review

September/October Issue of Becker's ASC Review

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61 Executive Briefing At Janssen, the Pharmaceutical Companies of Johnson & Johnson, we're creating a future where disease is a thing of the past. We tackle society's most pressing health challenges, connecting big ideas to the resources we need to make them a reality. Our goal is to advance access to good health for all. By seeking out medical breakthroughs wherever they occur, leveraging internal expertise and embracing external science, we aim to bring the best solutions to the people who need them. We focus our efforts and resources where the need is high, the science is compelling and where we have the greatest opportunity to save and improve lives. We go beyond the medicine by working with patients through the entire process to ensure the best possible experience and health outcomes. We are driven by our belief that "patients are waiting" and there is no time to waste. Learn more: www.janssen.com ix. Schreiner, P., Neurath, M. F., Ng, S. C., El-Omar, E. M., Sharara, A. I., Kobayashi, T., Hisamatsu, T., Hibi, T., & Rogler, G. (2019). Mechanism- Based Treatment Strategies for IBD: Cytokines, Cell Adhesion Molecules, JAK Inhibitors, Gut Flora, and More. Inflammatory intestinal diseases, 4(3), 79–96, pg 88. https://doi.org/10.1159/000500721 x. Lin, L., & Zhang, J. (2017). Role of intestinal microbiota and metabolites on gut homeostasis and human diseases. BMC immunology, 18(1), 2, pg 1. https://doi.org/10.1186/s12865-016-0187-3 xi. Groschwitz, K. R., & Hogan, S. P. (2009). Intestinal barrier function: molecular regulation and disease pathogenesis. The Journal of allergy and clinical immunology, 124(1), 3–22, pg. 10. https://doi.org/10.1016/j.jaci.2009.05.038 xii. Roda, G., Chien Ng, S., Kotze, P.G. et al. Crohn's disease. Nat Rev Dis Primers 6, 22 (2020), pg. 4. https://doi.org/10.1038/s41572-020-0156-2 xiii. Groschwitz, K. R., & Hogan, S. P. (2009). Intestinal barrier function: molecular regulation and disease pathogenesis. The Journal of allergy and clinical immunology, 124(1), 3–22. pg. 14. https://doi.org/10.1016/j.jaci.2009.05.038 xiv. Roda, G., Chien Ng, S., Kotze, P.G. et al. Crohn's disease. Nat Rev Dis Primers 6, 22 (2020). Pg. 4. https://doi.org/10.1038/s41572-020-0156-2 xv. Roda, G., Chien Ng, S., Kotze, P.G. et al. Crohn's disease. Nat Rev Dis Primers 6, 22 (2020). Pg. 7. https://doi.org/10.1038/s41572-020-0156-2 xvi. Roda, G., Chien Ng, S., Kotze, P.G. et al. Crohn's disease. Nat Rev Dis Primers 6, 22 (2020). Pg. 11. https://doi.org/10.1038/s41572-020-0156-2 xvii. Roda, G., Chien Ng, S., Kotze, P.G. et al. Crohn's disease. Nat Rev Dis Primers 6, 22 (2020). Pg. 5. https://doi.org/10.1038/s41572-020-0156-2 xviii. Groschwitz, K. R., & Hogan, S. P. (2009). Intestinal barrier function: molecular regulation and disease pathogenesis. The Journal of allergy and clinical immunology, 124(1), 3–22. pg. 7. https://doi.org/10.1016/j.jaci.2009.05.038 xvii. Schreiner, P., Neurath, M. F., Ng, S. C., El-Omar, E. M., Sharara, A. I., Kobayashi, T., Hisamatsu, T., Hibi, T., & Rogler, G. (2019). Mechanism- Based Treatment Strategies for IBD: Cytokines, Cell Adhesion Molecules, JAK Inhibitors, Gut Flora, and More. Inflammatory intestinal diseases, 4(3), 79–96. pg. 84. https://doi.org/10.1159/000500721 xix. Wehkamp, J. & Stange, E. F. (2020) An Update Review on the Paneth Cell as Key to Ileal Crohn's Disease. Frontiers in Immmunolgy, 11: 646. https://doi.org/10.3389/fimmu.2020.00646 We are Janssen Immunology. Innovating for patients around the world. 21 YEARS 5 TREATMENTS 30 INDICATIONS 5 million PATIENTS TREATED Join us at careers.jnj.com

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