A key to choosing the appropriate bone graft is understanding how well it works. Cerapedics has created
a revolutionary new category of spinal bone grafts with i-FACTOR that contains P-15 Peptide.
As a Class III drug-device combination product, i-FACTOR is the FIRST spinal bone graft driven by P-15
Osteogenic Cell Binding Peptide, which produces solid fusions by attaching and activating osteogenic
cells directly at the fusion site.
1,2,3,4
REFERENCES: 1. Hennessy KM, Pollot BE, et. al. Biomat 2009; 30(10): 1898-909. 2. Nguyen H, Qian JJ. et. al. Biochem
Biophys Res Commun 2003; 311(1): 179-86. 3. Yang XB, Bhatnager RS. et. al. Tissue Eng 2004; 10(7-8): 1148-59. 4.
Qian JJ, Bhatnager RS. et. al. J Biomed Mater Res 1996; 31(4):545-54. 5. Kesteloot G, Parish AJB. et. al. Poster, Annual
Scientific Mtg Belgian Soc Neurosurg 2016. 6. Arnold P, Sasso R. et. al. Spine 2016; 41(13): 1075-83. 7. Arnold P, Sasso
R. et. al. Neurosurg 2018; 83(3): 377-84.
ML-0625 06/20
Increased Cellular Proliferation & Protein/Matrix Production
1,2,3,4
Robust Fusions Similar to Mature & Healthy Bone
5
Superior Overall Clinical Success Compared to Autograft
6,7
Enhanced Cell Attachment and Increased Cellular Concentration
4
Attachment to
P-15 Peptide
Osteogenic Cell Receptor Integrins
Visit info.cerapedics.com/beckers for more information.
i-FACTOR® is the FIRST Bone Graft Powered by
P-15 Osteogenic Cell Binding Peptide
