Becker's Spine Review

22 DEVICES & IMPLANTS 5 big spine device companies making deals in 2019 By Alan Condon Several big transactions occurred in the spine device market in 2019. Here are five big spine device companies making transactions in 2019. Stryker acquired Mobius Imaging and sister company Cardan Robotics for $500 million in October. Stryker intends to use the imag- ing and robotic technologies of Mobius and Cardan to boost its presence in the spine, or- thopedic and neurotechnology markets. e acquisition grants Stryker's spine division access to the intraoperative imaging sector and aligns with its navigation and implant portfolio. Earlier this year, Stryker also acquired Or- thoSpace, an Israel-based company focused on technology to treat irreparable rotator cuff tears, for $10 million cash up front and $110 million if the company meets future mile- stones. Smith+Nephew acquired Osiris erapeutics, a bone gra and articular cartilage substitute products company, for $660 million in March. Osiris products include Grafix, a cryopre- served placental membrane skin substitute that treats acute and chronic wounds, as well as BIO4 bone matrix for bone repair. e compa- ny's product portfolio also includes Cartiform, an allogra for articular cartilage repair. e company also acquired Brainlab, boost- ing its orthopedic joint replacement business. Smith+Nephew will begin integrating the Brainlab platform into the next version of its robotic surgery platform, Navio 7.0. In late October, Johnson & Johnson Medical Shanghai entered into a co-marketing agree- ment and research and development agree- ment with the orthopedic robotics market leader in China, Tinavi. e deal allows the company to bring Tinavi's spinal and trauma robotic solution to the China orthopedics implant market. Tinavi's robotic platform in- cludes a robotic arm, intraoperative planning interface and integrated navigation with in- traoperative 3D imaging. DePuy Synthes will acquire the assets of JointPoint in a deal that is set for completion by the end of the year. e company will ac- quire JointPoint's navigation soware, which it plans to develop for further orthopedic pro- cedures. Neither company disclosed financial details of the deal. RTI Surgical completed the up to $300 mil- lion acquisition of Paradigm Spine in March. Paradigm Spine's flagship product, the coflex Interlaminar Stabilization device, is designed to treat moderately severe lumbar spinal ste- nosis in conjunction with decompression. RTI's existing spine portfolio consists of hard- ware, interbody and biologic options. n Medtronic Q2 spine revenue up 5.5%, Titan Spine adds $16M: 5 notes By Laura Dyrda M edtronic reported $7.7 billion revenue for the second quar- ter of the 2020 fiscal year, a 3 percent increase year over year, and Titan Spine added $16 million. Five things to know: 1. Medtronic closed the acquisition of Titan Spine earlier this year and it joined the company's spine division in the restorative therapies group, which reported a 6 percent increase in revenue to $2.1 billion. 2. Medtronic's spine division revenue was up 5.5 percent to $692 mil- lion, and combined with its robotic, navigation, imaging and power surgical instruments used in spine, global and U.S. revenue was up in the high single digits. 3. The cervical spine products revenue was up in the mid-single digits, driven by Infinity OCT system and Prestige LP cervical disc system sales. 4. Both spinal robotics, with the Mazor technology, and Infuse bone graft sales grew in the low-double digits. 5. Pain therapies was relatively flat at $315 million in quarterly reve- nue. Medtronic's Kyphon balloon kyphoplasty and OsteoCool radiof- requency ablation system sales drove low-double-digit growth for the interventional pain business. However, the pain stimulation sales de- clined due to a slowdown in the market. n Medacta, Geisinger expand lifetime guarantee of total hip, knee replacement surgeries By Alan Condon D anville, Pa.-based Geisinger and Me- dacta extended their lifetime guarantee for total hip and knee replacement surgeries to include revision knee surgeries Nov. 8. The guarantee covers failed knee replacement surgeries even if the initial procedure was per- formed outside the Geisinger health system or with joints that are not developed by Medacta. The organizations will cover the cost of care of the revision procedures as long as patients re- main in the care of a Geisinger provider and are a Geisinger Health Plan member. Geisinger began offering lifetime guarantees for eligible total hip replacements through an initiative with Medacta in 2018. n

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