Issue link: https://beckershealthcare.uberflip.com/i/1194306
18 Executive Briefing MAP-Bayesian software platforms like InsightRX, the guidelines call for using this software as the standard of care. It seems that the world is now ready for both precision medicine and precision dosing. DJ: What is InsightRX's approach to precision dosing, and how is it unique? JF: The first differentiator is the MAP-Bayesian forecasting. It enhances clinicians' ability to interpret information — for example a drug level — by offering the context of what could be expected based on pharmacokinetic models. This is incredibly powerful and is proven to improve the ability to dose drugs correctly. InsightRX also uses continuous learning. Today, we have a general idea of how we think patients should respond pharmacokinetically. We expect the drug to move through their body in a certain way, based on their age, size, gender, lab markers, etc. All of this is all summarized mathematically in a pharmacokinetic model. But we know that the models aren't perfect. That's why we get drug levels: every patient is a little different, and the models don't describe every person perfectly. InsightRX uses that data to improve the models themselves. It's possible that patients will respond differently based on factors like ethnic heritage, age, disease state or genotype, among others. These factors are analyzed and used to improve the models, so that when a similar patient is presented, we are that much more likely to get the right dose the first time. This learning cycle continues in perpetuity until there is a model that describes everyone, resulting in the exact dosing for every patient from day one. DJ: What are the main benefits of using precision dosing? JF: As with anything in healthcare, the goal is to get patients healthy as quickly and safely as possible. When you compare InsightRX to other means of monitoring, you're also able to achieve these goals with fewer measured drug samples, which means less phlebotomy and less pokes for your patient. In adults this can really improve patient satisfaction, but one less blood draw may prevent a baby from needing a blood transfusion later on. DJ: Why did InsightRX choose to partner with Premier? JF: This was a natural partnership. Premier is a well- respected organization, committed to facilitating and advancing the ability for healthcare providers to improve patient care. By aligning with Premier, we are able to bring precision dosing to even more hospitals and health systems across the United States. Making the partnership even more exciting for us was the ability to integrate with the patient chart through Premier's clinical surveillance solution, which is powered by TheraDoc®. We are thrilled to be working with the fabulous team at Premier and look forward to working together for years to come. LEARN MORE: theradoc.com/partners/ Premier Inc. is a leading healthcare improvement company, uniting an alliance of more than 4,000 U.S. hospitals and health systems and approximately 175,000 other providers and organizations to transform healthcare. With integrated data and analytics, collaboratives, supply chain solutions, and consulting and other services, Premier enables better care and outcomes at a lower cost.