So
ft
Ca
ll
us
Ha
r
d
Ca
ll
us
He
m
a
t
o
m
a
Bone and Tissue
Healing Phases
Bo
ne
Re
m
ode
li
ng
OSTEOAMP
BMP-5
Activin
A
aFGF
BMP-2
TGF-β2
ANGPT1
BMP-6
TNF-a
BMP-7
VEGF
SDF-1
ANG
TGF-β1
bFGF
PDGF-BB
TGF-β3
IGF-2
EGF
HB-EGF
IGF-1
ANGPT2
BMP-4
BMP-9
TNF-a
TGF-β1
Essential Growth Factors Supporting Bone Formation
Recent studies show that OSTEOAMP, as a result of our proprietary method
of processing bone with bone marrow, retains multiple growth factors that
are present at each phase of the natural bone healing process
1
.
1. Bioventus Surgical. Tidwell JL, Seaman SA, Vanderploeg EJ, Tom S. In vitro and in vivo characterization of OSTEOAMP allogeneic
morphogenetic proteins. Data on file, Bioventus white paper ; In vitro performance may not be predictive of performance in humans.
OSTEOAMP is a registered trademark of Bioventus LLC. All registered trademarks are the respective property of their owner. SMK-002469 | 8/18
S U R G I C A L
BioventusSurgical.com
Visit us at
NASS Booth
#1849
